O.J. Simpson, the former NFL star and broadcaster whose athletic achievements and fame were eclipsed by his 1995 acquittal in the brutal killings of his ex-wife Nicole Brown Simpson and her friend Ron Goldman, has died of cancer.

The family announced on Simpson’s official Twitter account that Simpson died Wednesday after battling prostate cancer. He died in Las Vegas, officials there said Thursday.

Simpson earned fame, fortune and adulation through football and show business, but his legacy was forever changed by the June 1994 knife slayings of his ex-wife Nicole Brown Simpson and her friend Ronald Goldman in Los Angeles. On June 12, the bodies of Brown Simpson and Goldman were found outside her condo in the Brentwood area of Los Angeles.

Simpson was a person of interest in the murders, but rather than turn himself in five days later, he led police on a low-speed chase throughout Los Angeles as a passenger in a white Ford Bronco driven by former NFL player Al Cowlings. An estimated television audience of 95 million watched the drama unfold, with live coverage interrupting regular programming, including the NBA Finals.